Optimal designs for the Michaelis–Menten model with correlated observations
نویسندگان
چکیده
منابع مشابه
Optimal designs for the Michaelis Menten model with correlated observations
In this paper we investigate the problem of designing experiments for weighted least squares analysis in the Michaelis Menten model. We study the structure of exact D-optimal designs in a model with an autoregressive error structure. Explicit results for locally D-optimal are derived for the case where 2 observations can be taken per subject. Additionally standardized maximin D-optimal designs ...
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ژورنال
عنوان ژورنال: Statistics
سال: 2013
ISSN: 0233-1888,1029-4910
DOI: 10.1080/02331888.2013.839680